H2 Library

Learn science behind the potential benefits of molecular hydrogen.


Hydrogen is an element with one proton and one electron and the simplest element in the known universe. Helium is created through the fusion of hydrogen. Hydrogen and helium together account for 99.9 % of all matter in the universe.

  • Hydrogen is the first element on the periodic table, with atomic number 1.
  • Hydrogen is present in water and in all organic compounds.
  • Hydrogen gas is colorless, odorless and tasteless.
  • Hydrogen gas is not flammable, unless the temperature exceeds 527oC and the concentration in air exceeds 4 % in volume.
  • When dissolved in water, hydrogen gas has a rating of 0/0/0 for health/flammability/instability on the Hazardous Material Information System.
  • Hydrogen gas has low water solubility, with the saturation concentration at normal conditions being around 1.6 ppm (1.6 mg H2 per liter).


  1. Ishibashi, T. et al., 2012. Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patient with rheumatoid arthritis: an open-label pilot study. Medical Gas Research, 2: 27. 
  2. Sakai, T. et al., 2014. Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. Vascular Health and Risk Management: 10: 591-597.
  3. Ishibashi, T. et al., 2015. Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases. Molecular Medicine Reports, 12: 2757-2764. 
  4. Nicolson, G.L. et al., 2016. Clinical effects of hydrogen administration: From animal and human diseases to exercise medicine. International Journal of Clinical Medicine, 7: 32-76.
  5. Dixon & Zhang, 2016. An Innovative collection in hydrogen molecular biology and medicine research. Medical Gas Research, 6: 55-56.
  6. Dole, M. et al., 1975. Hyperbaric hydrogen therapy: a possible treatment for cancer. Science, 190: 152-154.
  7. Shirahata, S. et al., 1997. Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage. Biochemical and Biophysical Research  234: 269-274.
  8. Ohsawa, M. et al., 2007. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nature Medicine, 13: 688-694.
  9. Ge, L. et al., 2017. Molecular hydrogen a preventive and therapeutic medical gas for various diseases. Oncotarget, 8: 102653-102673.
  10. Shimouchi, A. et al., 2009. Breath hydrogen produced by ingestion of commercial hydrogen water and milk. Biomarker Insights, 4: 27-32.
  11. Abraini, J.H. et al., 1994. Psychophysiological reactions in humans during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture. Journal of Applied Physiology, American Physiological Society, 76: 1113-1118. 
  12. Newcomer, A.D. et al., 1975. Prospective comparison of indirect methods for detecting lactase deficiency. New England Journal of Medicine, 293: 1232-1236.
  13. Metz, G. et al., 1976. Breath-hydrogen test for small-intestinal bacterial colonisation. Lancet, 1: 668-669.
  14. Rhodes, J.M. et al., 1979. The lactulose hydrogen breath test as a diagnostic test for small-bowel bacterial overgrowth. Scandinavian Journal of Gastroenterology, 14:333

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One of a kind indeed – Super Saturated Hydrogen Water

One of a kind indeed – Super Saturated Hydrogen Water